MedPage today story.
Public health officials in reports are looking for a possible rise in influenza nervous complications in children – especially a rapid and serious condition called acute necrosis (ANE).
Adrian Randolph, MD, Master at Boston Children’s Hospital, said that she had reported about 12 possible cases of influenza to the National Evance Center and Respiratory Diseases (NCIDD) in the past few weeks.
Randolf’s position as a leader Children’s intensive care network It gives it a special look at what is happening with the complications of influenza in children throughout the country.
Randolph told Randolph: “There is no study saying that all of these cases are all acute in the brain. MedPage todayUrging caution to take preliminary conclusions. “That is why I reported the Center for Disease Control of Possible Cases throughout the United States that I am aware of it. They can investigate.”
She noted that ANE can be a complex diagnosis, which requires some clinical features as well as photography results. For this reason, “all that is done in a systematic way must be done, as cases are carefully seen by experts.”
However, Randolph said she had not remembered any investigators from her sites monitoring any ANESE -related to influenza last year.
A spokesman for the Center for Disease Control MedPage today The agency “realizes the ane -like ane ane in children. “We do not have an active monitoring of ANE, but we are looking at the situation and we will make updates.”
Randolph said that her NCIDD’s contacts “asked me smart questions, and I sent them more information, and that is to a large extent.”
A doctor at one American center said MedPage today Their attachment had a child who dies from Influzia associated with influenza this year. “It has already advanced and it is [went into a coma] The source, whose name and location were blocked to protect the patient’s privacy, said that he died due to the complications of this.
Andrew Silverman, MD, MHS, and Keith Van Harin, PhD in Medicine, Stanford Medicine in California, said they are aware of at least 10 cases of influenza -related ANE in their state alone during influenza seasons this year.
“Although ANE is not a condition that can be reported specifically, this appears to be a real increase in the number of cases,” Silverman told Silverman. MedPage today. Last year, they treated a child because of the influenza -related ANE at Lucile Packard Children Stanford, and they were published Case report in neurology.
This case was followed by “an extraordinary group of additional cases during the next few weeks, which prompted interest in a larger case series.” MedPage today.
Silverman and Van Haren collect ANES -related ANES, and recently issued a request on the email lists of the international infectious diseases. Silverman said that with the assistance of the California Public Health Ministry, they also request monitoring recommendations for this situation.
Soo Hong Rotson, a doctorate in medicine, an ANE symptom that can include seizures and change the mental condition, said, and patients can become a coma.
“This type of amazing brain edema, as the brain enlarges very quickly in a really short time frame,” Rutson told Routson. MedPage today. “The child can walk to the hospital, and after a day or two, the brain is so swollen so much that it loses all the functions of the brain. It is a very terrifying entity because he feels when the domino begins to shift, it is really difficult to return from it.”
She said that ANE’s classic photography results include bilateral sharing, the sharing of deep gray matter, and sometimes the involvement of the brain stem.
Rotson said that its facility was exposed to one case of ANE this year, along with four other cases of children with neurological complications from the influenza that did not have classic ANE results on MRI or clinical progress.
She usually sees that she might be a single state of influenza with nervous complications every year: “It seems that we see many brain problems this year more than I saw in the past,” she said.
She noted that “it was a very active influenza season” with “a lot of influenza associated [intensive care unit] Acceptance “is happening now.
In fact, CDC data appears influenza in The highest level everGoing out to the PandeMic H1N1 2009-2010 season, tell the CDC source to not disclose his identity MedPage today. The source said: “The percentage of outpatient visits included in influenza -like disease starting from the week ending February is the highest ever, including the H1N1 of 2009.”
Experts said it is not clear whether the total influenza increase could lead to an increasing number of rare complications. There is also a possibility to vaccinate less, or perhaps less immunity because children may be exposed to influenza during the Covid-19s.
Last year, Italian researchers reported the outbreak of influenza with ANE at Mayer Children’s Hospital in Florence, Italy. Seven children developed the condition, starting from the most moderate brain disorders to ANE with a failure in coma and multiple failure, They detailed in the European CDC magazine, EurosurVeillance.
One of the children died and another left in a minimum, while the rest had a good or complete recovery.
The authors have reported that all children have experienced positive for the 2009 epidemic dynasty in H1N1, although it was not completely clear the cause of the group of cases.
Doctors were alert with the spread of the H5N1 bird influenza through dairy herds and poultry herds throughout the United States, with human issues reached a total of 68, According to the latest CDC data.
However, Randolph noted that any possible increase in the influenza nervous complications this year does not seem to be associated with H5N1. She said that many of the 12 cases in which she informed the Center for Disease Control had a sub -type, and it turned out that it was the 2009 PandeMic H1N1 breed.
However, sources at the Disease Control Center said that she feels in the dark of influenza monitoring, as it was not allowed to communicate with major partners such as medical organizations.
The source said: “Usually we communicate with our clinical partners and others at the present time, but we cannot speak to any of them because we were ordered to excavate by the new executive branch management.”
When it comes to H5N1 in particular, the source said that the Center for Disease Control does not get enough information about the test or the sub -type, “and therefore we do not understand the situation well.”
Randolf and Sorison said that ANE treatment, as it is believed to be an exaggerated reaction to the immune system, includes steroids, intravenous immunoglobulin, and other immune rates such as Anakinra (KINERET) and Tocilizumab (Actmra).
They pointed out that obtaining the word about a possible rise in cases may help community doctors to determine the condition and treat it better.