Credit
A genetically modified pork was planted in a person for the first time1. The recipient, a 39 -year -old man in China, died in the brain, but the member survived for nine days.
At least half of the decorations in the United States and China received organs of pigs freed by the genome, including hearts, kidneys, liver and thymus. The researchers say that the last procedure indicates that almost any port of pigs can be planted into people. They hope that one day animal organs will save thousands of people who die every year while waiting for a grant member.
Mohamed Mohnoin, surgeon and researcher at the University of Maryland Medical College in Baltimore, who led the first swine transplant to a living person. Mohuddin says the lungs have most of the blood vessels for any a cultivated organ, so they are more likely to attack the immune system, which may lead to blood clots and tissue damage. “I salute their efforts,” says: “It is a first step” towards lung transplantation, and the use of organs of other types in humans. American clinical trials of pigs and pigs have been approved this year.
Evidence of the concept
The left lung planted from a pig with six genetic adjustments created by the Chengde Clonorgan research company in China. This included removing three genes to reduce the risk of an immune response and add three human genes to protect the organ from rejection. In the experience of proof of concept, the lung was planted on May 15 last year, by researchers at the first dependent hospital at Guangzhou Medical University in China. Their results were published this week in Nature Medicine.
The team states that there are no signs of rejection, infection, or illegal gain failure in the first three days after surgery. However, 24 hours after the transplant, they noticed that the lung was swelling, and that the tissues were also damaged by going without oxygen for a period of time during the transplant. They also noticed damage caused by the antibodies that attack the member on the third and sixth day, but they indicated that the damage to the lung had decreased on the ninth day, when the study was stopped at the request of the recipient’s family.