Blockage-1 peptide-1 alarms, also known as GLP-1, such as semaglutide-known as OzemPIC-popular worldwide, have not only managed to manage type 2 diabetes but also because of the benefits of weight loss. This increase in popularity is mainly due to the approvals of celebrities and the strength of social media. According to Search letter It was published last year, the number of poultry -filling increased by 442 % between 2021 and 2023. OzemPIC represents more than 70 % of these fillings.
Its popularity has affected the segmentation of the sentence Costco Sell OzemPIC And wegovy (semaglutide is another famous) in a pharmacy for customers without health insurance at a high rate of $ 499 per month. according to GoodrxWegovy can cost $ 1,590.47 and OzemPic 1,216.69 dollars at full price.
Besides type 2 diabetes and weight loss, GLP-1 stimuli can also help lower blood pressure, improve fat disorders, reduce inflammation and improve heart health. With these advantages, the demand for GLP-1 stimuli continues to grow, making them one of the most expected treatments today.
What are the GLP-1 alarms?
GLP-1 stimulants, also known as the two metaphors, are a category of medications that are used primarily to treat type 2 diabetes, and in some cases of obesity.
This process on regulating blood sugar levels said: “Glp-1 is a natural hormone that occurs in the small intestine that leads to the release of insulin from the pancreas. This process helps to regulate blood sugar levels.” Angela Heinz FerryAssociate Professor at Emory Nursing School in Atlanta. “The GLP-1 mimics the functioning of this hormone that occurs naturally. After eating, the blood sugar level will rise, and these medications cause more insulin, which helps reduce blood sugar.”
In addition to helping people with type 2 diabetes in blood sugar, this drug reduces one appetite. It also slows down the digestive system, so that patients are up to feel full with less food. This leads to weight loss for many users, but it differs based on many individual factors.
According to Cleveland Clinic, most GLP-1 stimuli available As a liquid medicine, it must be injected under the skin, except for intake in the form of a diskus (Rybelsus).
A few General names and brands From the GLP-1 opponents, according to the Johns Hopkins Patient for Diabetes, including:
- Duclutide, has been marketed
- Lixisenatide, which is marketed as Adlyxin
- Liraglutide, marketed as vicoza
- Semaglutide, which is marketed as OzemPIC
- Plaglootide blade, which is marketed as Rybelsus
- Tirzepatide, which is marketed as Mountrao or Zepbound (Nahed-1/GIP double)
Each brand has a recommended and repeated dose. Some may be taken once a day, while others are used per week. You should consult your doctor to understand what the dose and frequency that suits you.
Possible GLP-1 benefits
“In addition to controlling blood sugar and reducing obesity, it has been proven that these drugs reduce the risk of cardiovascular and improves kidney function,” said Heinz Ferry. She noted that individuals report a decrease in smoking and gambling, consuming alcohol and drug use.
“Studies have shown benefits in exacerbation of kidney disease, heart failure, and sleep breathing in obese patients,” he says, he says, he says Dr. Lyon JunonWeight Management Specialist and Clinical Associate Professor in Oxyine internal medicine and metabolism at the Carvef College of Medicine in Iowa.
According to Cleveland Clinic, and the other benefits It may include GLP-1 stimuli:
- Lower
- Improving fat disorders
- reduction Seritis inflammation
- Delaying the development of kidney disease associated with diabetes or kidney disease associated with diabetes, also known as DKD
These benefits do not make the GLP-1 alarms only effective to manage type 2 diabetes but also contribute to improving cardiovascular health. However, the effect of GLP-1 alarm is different from person to person. Always talk to your doctor to understand how GLP-1 can stimulants benefit from your specified condition.
The side effects are GLP-1 alarm and risks to look at
For some patients, the speed of weight loss can lead to the unwanted aesthetic effect of the imaginary face (called colloquial “the face of the zemet”), especially in patients with elasticity of the skin. She added that regular exercise with weightlifting can help maintain muscle mass and maintain a healthy appearance.
The side effects of the drugs are often associated with the digestive system – for example, nausea, constipation, diarrhea or scattering. For most patients, these effects are moderate and solved over time. For some, the side effects can be severe, and patients will need to stop the drug.
Another common Side effects From the GLP-1 opponents, as stated in the article of a national library of medicine, including:
- Anorexia
- Vomiting
- headache
- dizziness
- Moderate tachycardia (increased heart rate)
In some cases, slight rings of blood sugar may occur. “Lack of blood sugar will be very rare and is likely to happen in patients who also take other drugs of diabetes that can reduce blood sugar too much,” said Dr. Troy Minsen, a family medicine doctor in the Chicago region and a member of the CNIT Medical Review Board. Cleveland Clinic stated that hypoglycemia is a condition in which glucose levels decrease Less than 70 mg/dl. If you are left without treatment, you may be threatening life. Symptoms of deficiency in fragile blood, weakness, nausea, difficulty concentration and dizziness may include. Consuming sugars or carbohydrates can treat blood sugar.
Also, doctors do not recommend GLP-1 alarms for congestion because they may pose a threat to the developing fetus. Consult your doctor if you are pregnant, or plan to become pregnant or breastfeed.
Who should take GLP-1 stimuli?
Doctors primarily recommend GLP-1 stimulants for type 2 diabetes and obesity. However, GLP-1 stimuli is not the first option for treatment. Metformin, oral medicine, remains The first choice To manage type 2 diabetes. However, doctors may recommend GLP-1 stimulants if you:
- MetVornin cannot be tolerated
- Unable to reduce blood sugar levels with continuous medications even after three months
- Experience complications due to other cases such as heart failure, atherosclerosis, or chronic kidney disease
Cleveland Clinic reported that doctors may also recommend GLP-1 alerts, Semaglutide and LiraglutideFor obesity. Dr. Minsen adds that Tirzepatide (Mounjaro or Zepbound), which is a dual GLP-1 GIP, may also be recommended.
“Based on the fact that every individual experience with this medicine varies, the patient must work with their health care provider to determine the best treatment plan and a goal of luxury in general,” said Heinz Ferry.
In addition, it has been proven that the GLP-1 alarms such as dulaglutide, semaglutide and liraglutide provide the benefits of cardiovascular and blood vessels. Doctors may also recommend these GLP-1 stimuli Reduce The risk of heart disease.
Recommended repetition Common GLP-1 stimuli include:
- Duclutide: Weekly
- Liraglutide: daily
- Semaglutide: weekly
- Tirzepatide: weekly
- Smojlotide tablets: daily
Who should not take GLP-1 alarms?
Although the GLP-1 alarms can help treat diabetes and obesity of type 2, they may not be suitable for everyone. Your doctor is permissible Avoid Description of GLP-1 stimuli if you have:
- Family History for Naked thyroid cancer: This thyroid cancer has been linked using GLP-1 stimuli in rodents. Your doctor may avoid describing the GLP-1 alarms if you have a family history of the noodles.
- Multiple deaf tumor syndrome type 2, or Men2: A rare condition with endocrine tumors. Doctors may avoid describing the GLP-1 alarms if you are diagnosed or have a family history of MEN2 because they can stimulate the growth of abnormal cells.
- Pregnant: Doctors may not recommend GLP-1 stimulants for pregnant women because it can pose a danger to the developing fetus.
- History of pancreatitis: Doctors often avoid GLP-1 stimulants in people with a history of pancreatitis because the GLP-1 risks may increase the risk of deadly hemorrhagic pancreatitis.
- Inflammatory or stomach bowel disorders: Glp-1 stomach stimuli emptying and symptoms of inflammatory bowel disorders may worsen.
Excess doses of GLP-1 and important information to be remembered
GLP-1 stimuli are prescription medications and should be taken only under the supervision of your doctor. Follow the recommended dose can help prevent excess doses. According to American poison centers, an overdose of the GLP-1 often Causes Similar symptoms of side effects:
- nausea
- Diarrhea
- Vomiting
- Abdominal pain
- holding
However, the duration of these symptoms may be longer. In severe cases, you may also face dryness and blood sugar, which may require immediate medical attention.
You should check the dose before taking the medicine and determine a reminder of the next dose to prevent the risk of an overdose.
When do you call the doctor?
You should contact your doctor if you have serious side effects after using GLP-1, such as:
- nausea
- Abdominal pain
- dizziness
- An increase in heart rate
- Vibrate
Also, consult your doctor first if you think the drug does not work for you or if you are considering not to continue the medicine.
In addition, regular schedule Follow -up With your doctor while you are in GLP-1 stimuli is important. This follow -up helps in monitoring blood glucose levels and determining whether any dose changes are necessary. Regular follow -up can also help doctors monitor the signs of hypoglycemia, kidney disease, pancreatitis and thyroid cancer.
The bottom line
GLP-1 stimuli are medications that primarily treat diabetes and type 2. However, recent studies indicate that they can reduce blood pressure, reduce inflammation and improve fat disorders. Many brands are available, each of which has its own dose guidance. However, the GLP-1 alarms may not be suitable for everyone. You should talk to your doctor to understand if you should take GLP-1 stimuli for your condition.