RNA-triggered Cas12a3 cleaves tRNA tails to execute bacterial immunity

Orthologue identification, phylogenetic analysis and sequence alignment We used previously identified Cas12a2 protein sequences27 as queries for tBLASTn and BLASTp ...
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Climate change shifts the North Pacific storm track polewards

Salathe, E. P. Influences of a shift in North Pacific storm tracks on western North American precipitation under global warming. ...
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Towards fibre-like loss for photonic integration from violet to near-infrared

Burmeister, E. F. et al. Photonic integrated circuit optical buffer for packet-switched networks. Opt. Express 17, 6629–6635 (2009). Article ADS ...
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Plastic landmark anchoring in zebrafish compass neurons

Animal husbandry The animal handling and experiments were performed according to protocols approved by the animal welfare officer at Institüt ...
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Prefrontal neural geometry of learned cues guides motivated behaviours

Pearce, J. M. & Bouton, M. E. Theories of associative learning in animals. Annu. Rev. Psychol. 52, 111–139 (2001). Article ...
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Chronic pain can be relieved by separating sensory and emotional experiences

Oswell, C.S et al. nature https://doi.org/10.1038/s41586-025-09908-w (2026). condition Google Scholar Grahik, N. Feeling pain and being exposed to pain First ...
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A young progenitor for the most common planetary systems in the Galaxy

Transit observations and analysis We analysed a heterogeneous dataset of light curves from space- and ground-based telescopes (Supplementary Table 1) ...
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Bidirectional CRISPR screens decode a GLIS3-dependent fibrotic cell circuit

Generating the integrated IBD scRNA-seq atlas Previously published scRNA-seq datasets on CD and UC were used for integrative analysis2,9,11,13. The ...
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Aharonov–Bohm interference in even-denominator fractional quantum Hall states

Feldman, D. E. & Halperin, B. I. Fractional charge and fractional statistics in the quantum Hall effects. Rep. Prog. Phys. ...
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Scientists are abandoning fieldwork in the age of artificial intelligence

Tadeo Ramírez Parada studied the flowering timing of plants while doing his PhD, but he never touched a single petal. ...
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