RNA-triggered Cas12a3 cleaves tRNA tails to execute bacterial immunity

RNA-triggered Cas12a3 cleaves tRNA tails to execute bacterial immunity
Orthologue identification, phylogenetic analysis and sequence alignment We used previously identified Cas12a2 protein sequences27 as queries for tBLASTn and BLASTp ...
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Climate change shifts the North Pacific storm track polewards

Climate change shifts the North Pacific storm track polewards
Salathe, E. P. Influences of a shift in North Pacific storm tracks on western North American precipitation under global warming. ...
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Towards fibre-like loss for photonic integration from violet to near-infrared

Towards fibre-like loss for photonic integration from violet to near-infrared
Burmeister, E. F. et al. Photonic integrated circuit optical buffer for packet-switched networks. Opt. Express 17, 6629–6635 (2009). Article  ADS  ...
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Plastic landmark anchoring in zebrafish compass neurons

Plastic landmark anchoring in zebrafish compass neurons
Animal husbandry The animal handling and experiments were performed according to protocols approved by the animal welfare officer at Institüt ...
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Prefrontal neural geometry of learned cues guides motivated behaviours

Prefrontal neural geometry of learned cues guides motivated behaviours
Pearce, J. M. & Bouton, M. E. Theories of associative learning in animals. Annu. Rev. Psychol. 52, 111–139 (2001). Article  ...
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Chronic pain can be relieved by separating sensory and emotional experiences

Chronic pain can be relieved by separating sensory and emotional experiences
Oswell, C.S et al. nature https://doi.org/10.1038/s41586-025-09908-w (2026). condition Google Scholar Grahik, N. Feeling pain and being exposed to pain First ...
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A young progenitor for the most common planetary systems in the Galaxy

A young progenitor for the most common planetary systems in the Galaxy
Transit observations and analysis We analysed a heterogeneous dataset of light curves from space- and ground-based telescopes (Supplementary Table 1) ...
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Bidirectional CRISPR screens decode a GLIS3-dependent fibrotic cell circuit

Bidirectional CRISPR screens decode a GLIS3-dependent fibrotic cell circuit
Generating the integrated IBD scRNA-seq atlas Previously published scRNA-seq datasets on CD and UC were used for integrative analysis2,9,11,13. The ...
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Aharonov–Bohm interference in even-denominator fractional quantum Hall states

Aharonov–Bohm interference in even-denominator fractional quantum Hall states
Feldman, D. E. & Halperin, B. I. Fractional charge and fractional statistics in the quantum Hall effects. Rep. Prog. Phys. ...
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Scientists are abandoning fieldwork in the age of artificial intelligence

Scientists are abandoning fieldwork in the age of artificial intelligence
Tadeo Ramírez Parada studied the flowering timing of plants while doing his PhD, but he never touched a single petal. ...
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