The ads on podcasts and social media were confusing: propiots that do not need a prescription can avoid the worst effects of alcohol headache if taken before drinking.
As a Bourbon auditor who had the flavor of lives but he was always vulnerable to backwardness, Eric Burke was fascinated. He has requested some pre -alcohol bottles, a probiotics drink from Zbiotics, to test them.
He dropped the mixture of water, salt and flavor and Genetically modified bacteria. He followed it with a cocktail, meal and two borbon, and woke up the next morning he felt much more than he expected.
The next night, I grew up due to success, drinking another bottle of half an ounce of alcohol. Drink a little more than the last night – beer with dinner and four of the acrobat from Bourbon.
This amount usually lets him feel pain and slow the next day.
This was exactly what he felt when he opened his eyes after hours.
“This was unpleasant. I woke up that morning,” well, I am no longer 21. “
Waste A group of physical and mental symptoms The result of inflammation and oxidative stress that results in alcohol in the human body.
One of the numerous factors that contribute to the misery of the day after the day is the accumulation of acetaldehyde, which is a chemical secondary result of ethanol drinks in the body. Acetaldehyde is a carcinogenic material that is characterized by nausea, stomach disorder, sweating and other physical symptoms associated with excessive consumption.
Both Zbiotics’ before alcohol and Swedish Biotechnology Company De Faire Medical AB Myrkl depend on the live bacteria to treat overpowering acetalhyde. last Researchers and They drink entertainment I also tried probiotics for similar purposes.
Reducing the amount of acetaldehyde, as the hypothesis says, must also reduce the physical symptoms caused by its accumulation.
A waiter carrying Martini with lemon.
(Myung J. Chun / Los Angeles Times)
“The more you drink, the more you have to deal with the effects of other things alongside acetaldehyde,” said Zak Abbott, CEO of Geockeex, by e -mail when asked about Burke’s results. “However, for the vast majority of people, acetaldhyde is a major factor, and therefore alcohol results in a feeling better (If not perfect) The next day. ”
The American Food and Drug Administration considers that Zbiotics and Myrkl are nutritional supplements or functional foods, not medications, and therefore do not evaluate their health claims. Microbium experts have warned that propi -supplements alone will not save you from the worst effects of excessive leniency.
For beginners, the bloodstream carries most of the ethanol in an alcoholic drink directly into the liver, where an enzyme is called alcohol dehydrogenease into acetaldhyde. The brain, the digestive system and the pancreas treat some alcohol as well. A relatively small amount of ethanol is met in the intestine, where probiotics do their job.
The addition of the probiotics to the pre -party system will not cause you any harm.
He said that it is unlikely to have a great impact on what you feel the next day, as your intestine has become pre -equipped with an army of bacteria capable of breaking alcohol products.
“There is not a lot of ethanol and asphalidheide in your large intestine to start,” said Zanaller, and “the vast majority of bacteria in your intestine already host acetaldhyde for you, so just add something else that may not be trick.”
Zbiotics has funded studies that show each of its products and that its bacteria have already collapsed a large amount of acetaldhyde in the intestinal simulation conditions in the laboratory. As for the effects in the real world of this collapse, Abbott referred to the outside 2006 paper This has found that the mice that gave ethanol have similar symptoms less than alcohol headache the next day when acetaldehyde was removed.
Myrkl made small funding Ticket This showed that its product has reduced alcohol levels in the blood in some participants. Topics were directed to Take the supplement for a week Before drinking, instead of the pre -party dose on the package.
He said the difficult truth Joris C. VersterProfessor of Pharmacy at Utrecht University in the Netherlands and founder Alcohol residue collection Consortium, is that there is currently one method that has been scientifically validated to prevent the remains of problems: drinking less alcohol.
“Although there are many alcohol headache products, there is no convincing scientific evidence that these treatments are effective. There is a need for independent dual -blind clinical experiences in those who drink social wine,” said Verster. “At the present time, the only effective way to prevent alcohol headache is to consume alcohol in moderation.”
He said that the leftovers are unpleasant because it serves a valuable purpose Dr. Daril DavisProfessor of Clinical Pharmacy and Director of Alcohol and Empering Research Laboratory at the College of Pharmacy and Pharmaceutical Sciences at the University of Southern California Man.
“What I tend to tell people is that if you get residue, you drink too much,” said Davis. “It is the body trying to tell you that there is something wrong.”